Anthropic’s Fable 5.1 Hits 60.9% on Humanity’s Last Exam, GPT-6 Astra Drops, & the Cybercab Takeover | Moonshots #286

Moonshots · Episode 286 · Host: Peter Diamandis · Guest: Emad Mostaque · Published Sep 5 2026 · Runtime 2:24:41 · Watch: YouTube

Peter, Dave, Salim, and Alex, with Emad Mostaque, on GPT-6 Astra, Fable 5.1, a kill switch, a superintelligence ban, and the Cybercab in Austin.

Chapters
  • 0:00 GPT-6 Astra and the Cybercab.
  • 1:27 Introducing the mates.
  • 7:11 GPT-6 Astra benchmarks.
  • 11:20 Safety, cybersecurity, and guardrails.
  • 24:29 Fable 5.1, Astra, and cost.
  • 34:34 Twin primes and grand challenges in math.
  • 43:10 Depth scaling and interpretability.
  • 45:42 Ilya on neoclouds.
  • 57:15 Infinite context window.
  • 57:48 Banning superintelligence.
  • 1:01:44 Fermat's last theorem, formalized.
  • 1:15:07 Atlas, a world model.
  • 1:35:40 Cybercab event in Austin.
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People

On this episode

Peter Diamandis

Host. 1:59

Dave Blundin

Host. 2:12:26

Salim Ismail

Host. 1:51

Alex Wissner-Gross

Host. 12:00

Emad Mostaque

Guest. Back on the show, calling from the Caribbean. 1:56

Don Musalem

Fountain Life's chief medical officer, in the health segment. 1:34:20

People mentioned

Sam Altman

Bloomberg clip on Astra. 8:20

Greg Brockman

Interview they cite on the Astra pre-train. 16:34

Ilya Sutskever

The neocloud tweet they read. 45:42

Bernie Sanders

The bill to ban artificial superintelligence. 57:48

Greg Casar

Introduces the ban bill with Sanders. 57:50

Elon Musk

On video at the G20, and the Cybercab. 59:10

Mark Zuckerberg

At the G20, arguing against restricting open models. 59:16

Tom Brown

Named as an Anthropic co-founder at the G20. Not on this call. 59:20

Fei-Fei Li

Atlas at World Labs. Not on this call. 1:15:07

William Shatner

Executive producer of the Star Trek 60th documentary they plug. 1:25:45

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Products

The Last Economy: A Guide to the Age of Intelligent Economics — Emad says they have been working on the last economy. Amazon 1:28:11

Hobie Cat Wooden Boat Kit by Dumas — closest Amazon match for the Hobie Cat beside Emad. Amazon 2:54

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Overview

Peter, Dave, Salim, and Alex sit with Emad Mostaque on GPT-6 Astra and Anthropic's Fable 5.1, OpenAI's kill switch, Bernie Sanders's ban on superintelligence, Fei-Fei Li's Atlas, and Tesla's Cybercab event in Austin.

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Places
PlaceType
Houston 2:21City
Caribbean 2:48Region
White House 42:22Building
Chapel Hill, North Carolina 58:29City
Austin, Texas 1:35:44City
Boston 1:43:27City
London 1:44:21City
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Ads
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