Martine Rothblatt: Growing Unlimited Organs, AI Consciousness, & Digital Personhood by 2030 | Moonshots #290

Moonshots · Episode 290 · Host: Peter Diamandis · Published Sep 15 2026 · Runtime 49:21 · Watch: YouTube

Peter Diamandis sits down one-on-one with Martine Rothblatt on thymus rejuvenation, organs on demand, AI consciousness, and digital personhood.

Chapters
  • 0:00 Why Rothblatt is the guest.
  • 1:55 Moonshots in space and biotech.
  • 3:54 How she picks which moonshot to chase.
  • 5:48 Criticism, and getting past it.
  • 10:00 Scaling a technology to billions.
  • 11:59 Longevity escape velocity.
  • 13:57 Rejuvenating the thymus.
  • 19:55 Organs on demand.
  • 22:13 Transplants and xenotransplantation.
  • 23:58 AI, digital personhood, and consciousness.
  • 31:50 Uploading a mind.
  • 36:04 Space settlements and Gerard O’Neill.
  • 38:48 Advice for founders.
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People

On this episode

Peter Diamandis

Host. Runs the one-on-one interview and the Fountain Life segment. 1:13

Martine Rothblatt

Guest. Founder of United Therapeutics and SiriusXM, on organs, the thymus, and digital minds. 2:17

People mentioned

Elon Musk

Named as the greatest living entrepreneur. Not on the call. 1:55

Gerard K. O’Neill

Named for the Space Studies Institute and O’Neill colonies. Not on the call. 1:23

Ray Kurzweil

Named as a mutual friend and United Therapeutics board member. Not on the call. 11:44

George Church

Named as the Harvard expert who said she could build lungs. Not on the call. 5:53

Arthur C. Clarke

Named for the line about wise old experts. Not on the call. 6:09

Robert A. Heinlein

Named for Time Enough for Love and the Heinlein Prize. Not on the call. 14:27

Nancy Manley

Named as the ASU thymus researcher. Not on the call. 18:18

Peter Zandstra

Named as the UBC aging-immunity researcher. Not on the call. 18:25

Demis Hassabis

Named for curing all disease in a decade. Not on the call. 25:37

Dario Amodei

Named for AI doubling the human lifespan. Not on the call. 25:41

David Sinclair

Named for epigenetic reprogramming work. Not on the call. 25:50

Marvin Minsky

Named as an early influence on digital minds. Not on the call. 27:45

Hans Moravec

Named alongside Minsky and Kurzweil. Not on the call. 27:46

Bina Rothblatt

Named as her wife, the model for the first digital doppelganger. Not on the call. 28:27

David Hanson

Named for building that first doppelganger. Not on the call. 28:32

Alex Wissner-Gross

Named by Peter as a moonshot mate who agrees on AI consciousness. Not on this call. 31:02

Javier Milei

Named for Argentina’s AI invitation. Not on the call. 31:49

Alan Dershowitz

Named for arguing AI legal rights in her film with Ray. Not on the call. 32:18

Pauley Perrette

Named as the actor who played Ramona. Not on the call. 32:21

Thomas Jefferson

Named as born at the wrong point in time. Not on the call. 33:45

Jared Isaacman

Named as Peter’s recent podcast guest. Not on this call. 38:52

Mark Zuckerberg

Named for a Wall Street Journal op-ed on AI fear. Not on the call. 45:59

Franklin D. Roosevelt

Named for nothing to fear but fear itself. Not on the call. 46:09

Warren Buffett

Named for saying no to almost everything. Not on the call. 48:25

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Products

Time Enough for Love — Heinlein’s novel, named for Lazarus Long’s renewal. Amazon 14:25

The Age of Spiritual Machines — Ray Kurzweil’s book, named as an early influence. Amazon 27:39

The Singularity Is Near — Ray Kurzweil’s follow-up, named in the same breath. Amazon 27:41

Virtually Human — Martine’s own book on AI personhood. Amazon 32:06

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Overview

Peter Diamandis sits down one-on-one with Martine Rothblatt on thymus rejuvenation, organs on demand, AI consciousness, and digital personhood.

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Places
PlaceType
Harvard Medical School 5:57School
Arizona State University 18:08University
University of British Columbia 18:13University
Christiansburg, Virginia 22:57City
Rochester, Minnesota 23:05City
Houston, Texas 23:10City
UCLA 29:12University
Argentina 31:49Country
Hollywood Bowl 32:25Venue
Ohio 40:10State
Princeton 40:43City
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