Ask the Mates Anything Round #2 | Moonshots AMA #293

Moonshots · AMA #293 Ask the Mates Anything Round #2 · Hosts: Peter Diamandis, Dave Blundin, Alexander Wissner-Gross, Salim Ismail · Published Sep 22 2026 · Runtime 1:26:11 · Watch: YouTube

Chapters
  • 1:08 Open — Peter and Alex at the table; AMA queue.
  • 2:09 Nathan — AI data and brain-pattern inference.
  • 5:12 Dave — AI watching AI; don’t slow the work.
  • 7:26 Ad — Google for Startups generative media.
  • 11:09 Norbert — p(doom) steelman; White House lawn case.
  • 20:29 Alex — lunar ISRU and a self-replicating fab.
  • 27:01 Peter — “show them the data” on longevity.
  • 33:49 Ad — Blitzy autonomous codegen.
  • 40:33 Dave — MBAs managing agents.
  • 50:01 Jim — Qwen under the desk as a pen-tester.
  • 57:23 Vision — Sinclair gene rewind vs Neuralink.
  • 1:24:50 Close — Solve Everything and Accelerando.
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People

Peter Diamandis

Host. Runs the AMA queue, the longevity evidence stack, and the close. 1:08

Dave Blundin

Co-host. AI-watching-AI, Ireland as a governance sandbox, agents for MBAs. 5:12

Alexander Wissner-Gross

Co-host. Lunar fab bottleneck, sandbox-lie critique, Accelerando close. 20:29

Salim Ismail

Co-host. Joins from Bangalore; universities, org learning loops, P(abundance). 37:53

Charles Stross

Alex’s close sci-fi pick for the transition: Accelerando. 1:24:50

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Products

Accelerando (Charles Stross) — Alex’s close sci-fi pick. Amazon 1:24:50

The Diamond Age (Neal Stephenson, paperback) — Dave’s variety-of-ideas cite. Amazon 17:23

2001: A Space Odyssey (Blu-ray) — Alex’s sandbox-lie / HAL lesson. Amazon 7:17

Person of Interest: The Complete Series — Norbert’s benevolent-optimization foil. Amazon 9:59

Solve Everything — Peter and Alex at the close. Official site 1:24:50

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Overview

Peter, Dave, Alex, and Salim take AMA callers through mind-reading models, AI that polices AI, a lunar fab, longevity evidence, and agent-era MBAs — Google, Blitzy, and Fountain Life in the breaks, Accelerando at the close.

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Places

Bangalore — Salim joins from a car after a stage set in India. 37:53

Ireland — Dave’s EU governance sandbox. 17:23

Moon — Lunar ISRU and a self-replicating fab. 20:29

Germany — Media-doomerism question; talent not in the AI race. 1:13:01

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